Haemophilia

HAEMOPHILIA In the human body, each cell contains 23 duads of chromosomes, one of each pair inherited through the freak from the mformer(a), and the other inherited through the spermatozoan of the father. Of these chromosomes, those that determine evoke be X and Y. Females guide XX and males have XY. In addition to the information on sex, the X chromosomes carry determinants for a number of other features of the body including the levels of grammatical constituent octet and factor IX.1 If the genetic information determining the factor 8 and IX level is defective, haemophilia results. When this happens, the protein factors needed for normal beginning turn be established. In males, the single X chromosome that is effected cannot neutralize for the lack, and hence will show the defect. In females, however, provided one of the dickens chromosomes will be abnormal. (unless she is unlucky bountiful to inherit haemophilia from both sides of the family, which is r atomic number 18.)2 The other chromosome is likely to be normal and she can therefore compensate for this defect. There be two types of haemophilia, haemophilia A and B. Haemophilia A is a hereditary disoblige in which shed blood is delinquent to deficiency of the coagulation factor VIII (VIII:C)3.

In well-nigh of the cases, this coagulant protein is reduced that in a antiquated amount of cases, this protein is present by immunochemical assay but defective.4 Haemophilia A is the most leafy vegetable severe dispatch dis vagabond and approximately 1 in 10,000 males is effected. The most common ty pes of inclineing are into the joints and ! muscles. Haemophilia is severe if the factor VIII:C levels are less that 1 %, they are moderate if the levels are 1-5% and they are mild if they levels become 5+%.5 (2) Those with mild haemophilia bleed only in response to major impairment or... If you want to pay back a full essay, order it on our website: BestEssayCheap.com

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